The Delaware Cancer Consortium was originally formed as the Delaware Advisory Council on Cancer Incidence and Mortality in March 2001 in response to Senate Joint Resolution 2 signed by Governor Ruth Ann Minner.

The advisory council, consisting of 15 members appointed by the governor, was established to advise the governor and legislature on the causes of cancer incidence and mortality and potential methods for reducing both.

The advisory council was later expanded and its name changed to the Delaware Cancer Consortium (DCC) in SB102. The Advisory Council continues on as a sort of steering committee for the consortium.